It seems that Plug In sound cards are disappearing. If you're going to do any recording, the USB interfaces work quite well. I have both a Scarlet 2i2 & a Native Instruments at home and both sound great. I've also just had my computer at work upgraded, and they had to go USB. Have a Steinberg interface there. While it works fine, it's locked at a bit depth of 24, which Adobe Audition 3.0 doesn't like. But, of course, the Audition Creative Suite (that requires a leased license) works fine.
Gary, sounds like you'll be fine running VAC. Especially if you're not trying to record anything.